Funding Priority

Unite Across Population Sciences to Beat Cancer

Cancer treatment and prevention goes beyond the research lab. As a global leader in population sciences, we must continue to use our understanding of social, behavioral, genetic, epidemiological and surveillance research to champion practices and policies that improve cancer prevention and control.

UNC Lineberger Comprehensive Cancer Center

    Solving in Sequence

    What if the most important answers for the future of humanity could be uncovered by looking within humanity itself? Although it’s not quite that simple, we are uncovering big solutions by looking into the genetic makeup of cancer patients across the state.

    Through Next-Generation Sequencing (NGS), we use high-powered sequencing technologies, massive data resources and other tools to assess how an individual’s genes influence the risk of developing cancer. Tumor samples obtained from biopsy or surgery are analyzed using NGS to identify the molecular or genetic changes that could influence outcomes or choice of therapy. UNCseqTM, a unique sequencing platform and clinical trial, enables our teams to create customized cancer treatment plans for new patients every day.

    Our leadership in cancer genetics has also led to our key role in The Cancer Genome Atlas, a National Cancer Institute, multi-institutional effort to characterize thousands of human cancer samples. We supported the project by sequencing RNA, the genetic code that carries instructions from DNA for making proteins. As of 2016, more than 100 trillion RNA bases and more than 10,000 tumor tissues have been sequenced at UNC Lineberger. Ultimately, this work will provide critical insights that will direct the development of new treatments that target a cancer’s genetic weakness.

    By looking within one another, we find great potential. Between advances in computer processing power and our growing understanding of individual genomes, we are poised for breakthrough after breakthrough.

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    Shelley Earp unc Lineberger
    Health

    Advancing Cancer Research and Care Across Carolina and the Globe

    As a nationally recognized cancer researcher and current director of UNC Lineberger Comprehensive Care Center, Shelton “Shelley” Earp is as comfortable in the lab as he is cheering for the Tar Heels in the Dean Dome.

    Research

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    UNC Lineberger designs, develops and delivers CAR-T therapy to to attack cancers.

    Patient

    From Cancer Patient to Volunteer

    “In this position I feel like I’ve been given a purpose, and I wouldn’t have had this opportunity before. To be a part of cancer therapies, even my own, is a very special thing.”

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    Winning His Battle, Helping Others Fight Theirs

    The Champ and ET Mitchell Fund for Blood Cancer Research will accelerate research at UNC Lineberger Comprehensive Cancer Center.

    Health

    Helping to unlock the mysteries of cancer

    "There’s no reason those discoveries can't be made right here in Chapel Hill."

    Health

    An Investment In People

    "This is an opportunity for us to continue our work investing in excellent education for the benefit of the entire state."